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Symbol
Name
ID 		Itga4
integrin alpha 4
MGI:96603
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Disease(s) Associated with ITGA4
pancreatic cancer

Mouse Phenotypes
abnormal leukocyte migration
abnormal cellular extravasation
abnormal leukocyte adhesion
abnormal definitive hematopoiesis
abnormal B cell differentiation
abnormal myeloblast morphology/development
decreased B cell number
decreased CD4-positive, alpha-beta T cell number
decreased T cell number
decreased lymphocyte cell number
increased leukocyte cell number
abnormal mononuclear cell morphology
abnormal reticulocyte morphology
Availability Mouse Genotype
Itga4tm1Mshi/Itga4tm1Mshi
Itga4tm1Tpa/Itga4tm1Tpa
Tg(Mx1-cre)1Cgn/?  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory